Neurotoxins 101: Where They're Placed and What Each Area Treats

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Dr. Chet Mays

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2/17/2026

Neurotoxins are one of the most popular aesthetic treatments for a reason - they're quick, effective, and require little to no downtime. But many patients don't realize just how customizable these treatments are.

Strategic placement matters. Where neurotoxins are injected determines not just what lines are softened, but how your overall facial expression is balanced and refreshed.

Here's a breakdown of the most common treatment areas - and what each one does.

Forehead Lines

Horizontal forehead lines form from raising your eyebrows over time.

What it does: Softens forehead lines while maintaining natural brow movement when dosed appropriately.

Goal: Smoother looking skin without looking frozen.

Frown Lines (The "11s")

The vertical lines between your eyebrows are often called "11 lines."

What it does: Relaxes the muscles that cause a furrowed or tense expression.

Goal: A more relaxed, approachable appearance.

Crow's Feet

These lines appear at the outer corners of the eyes when smiling.

What it does: Softens fine lines while preserving a natural smile.

Goal: Brighter, more youthful-looking eyes.

Brow Lift

Small, precise injections can subtly elevate the tail of the brow.

What it does: Creates a more open, refreshed eye area.

Goal: Gentle lift without surgery.

Bunny Lines

These are the small wrinkles that appear on the sides of the nose when you smile or scrunch.

What it does: Softens scrunch lines for smoother skin around the mid-face.

Lip Lines

These are the small vertical lines that form above the upper lip from puckering, smoking, or repetitive movement like drinking through a straw.

What it does: A small amount of neurotoxin placed around the lip border can soften dynamic puckering lines and reduce deep creasing over time.

Goal: Smoother lip lines while preserving natural movement for speaking and smiling.

Lip Flip

A small amount of neurotoxin placed along the upper lip border.

What it does: Allows the upper lip to gently roll outward, creating the appearance of more lip without filler.

Goal: Subtle volume enhancement in the upper lip.

Downturned Smile (DAO Treatment)

If the corners of your mouth pull downward at rest, it can create a sad or tense appearance.

What it does: Strategic placement of neurotoxin into the DAO muscle relaxes the downward pull, allowing the corners of the mouth to sit more neutral - or slightly lifted.

Goal: A softer, more positive resting expression without changing your natural smile.

Chin (Pebbled Chin)

Some people develop dimpling or texture in the chin when speaking or resting.

What it does: Smooths dimpling and softens tension in the lower face.

Jawline Slimming/TMJ Relief

Neurotoxins can be placed in the masseter muscles (jaw muscles).

What it does: 

  • Softens jaw clenching and grinding 
  • Can slim a wider lower face over time

Goal: Facial balance and functional relief.

Neck Bands

Vertical bands in the neck can become more noticeable with age.

What it does: Relaxes platysmal bands for a smoother neck contour

The Key Is Customization

Neurotoxin treatment is not one-size-fits-all. The right placement, dosage, and combination of areas depend on: 

  • Your facial anatomy 
  • Muscle strength 
  • Desired outcome 
  • Whether you prefer subtle softening or more dramatic smoothing

At The Spa at MPS, treatments are designed to maintain natural expression while enhancing balance and softness.

Not Sure Where You Need It?

Many patients come in thinking they only need one area treated, but after evaluation, we may recommend small adjustments in complementary areas to create more harmonious results.

A consultation allows us to: 

  • Assess muscle movement 
  • Discuss your goals 
  • Create a personalized treatment plan

Subtle changes, when placed strategically, can make a significant difference

Ready to Find the Right Placement for You?

Neurotoxin treatments are most effective when they're customized to your unique facial anatomy and goals. Whether you're concerned about forehead lines, a downturned smile, lip lines, or jaw tension, the right placement makes all the difference.

A consultation at The Spa at MPS allows us to evaluate your muscle movement, discuss your concerns, and design a treatment plan that keeps you looking natural - just more refreshed. If you've been thinking about it, this is your sign to schedule your consultation  and get personalized guidance from our expert injectors.

Mays Spa is my HAPPY place for the serene ambiance, their kindness, and the fabulous services I've had (Botox, Cool Peel, facials, derma planing, etc.), but Trina is simply "aMAYzing" as an expert in Botox injections. Her extensive medical background as a registered nurse gives her precise knowledge of the intricate facial muscles and how they work together to restore and maintain a soft & youthful look in her patients. I came to her desperate for help after an 8-year struggle with very obvious asymmetry in my face after a severe case of Bell's palsy in 2018. I couldn't smile normally or completely close my left eye, even after seeing countless medical doctors, ENT and facial nerve specialists, other Botox injectors, and many years of acupuncture on my face. No treatment made much difference until I found her at Mays Spa. She is a **miracle worker**, but I'll let the before and after photos speak for themselves (attached to post). Trina has exponentially improved my quality of life (after all, your face is your calling card), and I adore her and the whole team at Mays Spa. Signed, a GRATEFUL school teacher.

K.B. Google

I had an amazing experience with Dr. Gross and his team! I recently had a CoolPeel laser treatment, and the results have been incredible. From the moment I walked into the office, I felt welcomed and comfortable. The office itself is beautiful, clean, and professional.Dr. Gross was friendly, knowledgeable, and made me feel at ease throughout the entire procedure. He consistently checked on my comfort level and explained everything clearly, which made the experience stress-free and enjoyable.The results exceeded my expectations. My skin looks brighter, smoother, and has a healthy glow. I could see a noticeable difference almost immediately after the treatment.I highly recommend Dr. Gross and his amazing staff to anyone considering laser treatments or other aesthetic procedures. The level of care, professionalism, and attention to detail was truly exceptional. 10/10 experience!

J.G. Google

Beautiful space! Very friendly staffGabby at the front gave us the best personalized experienceShe needs a raise!!!!Iconic

R.A. Google

Ashley H is amazing! After I got the diamond glow my skin looked so good and felt refreshed! It was very relaxing! 100% recommend

F.W. Google

Ashley is so wonderful and knowledgeable about skincare! All the staff are so nice and kind!

G.K. Google

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* All information subject to change. Images may contain models. Individual results are not guaranteed and may vary.